Ferti-Jin Women's Health and IVF Center Clinical Director, Women's Health and Diseases, IVF Specialist Op. Dr. Seval Taşdemir: “Increasing cancer diseases do not prevent your dreams of having children. You can freeze your eggs or embryos before chemotherapy and radiotherapy treatments. This way, you can achieve your baby's dream after cancer treatment. ”In what circumstances does cancer treatment harm reproduction? Chemotherapy and radiotherapy used in childhood and fertility cancers damage reproduction. Types of cancer in fertility period; breast, cervix, cervix, ovary and thyroid, childhood leukemia and blood diseases that require bone marrow transplantation, intensive chemotherapy is important, the protection of fertility is important from this age. The type, duration, dose and effect of the drug used vary according to age. Especially the agents used in chemotherapy and radiotherapy to the uterus-ovary region damage the reproductive cells. What methods do you use against cancer infertility? The infertility method depends on whether the patient is married or not. If the patient is single, it is preferable to freeze the egg or ovarian tissue. In egg freezing, the ovaries are grown and collected before chemotherapy (approximately 15 days in advance) by stimulating the drug and frozen before fertilization. Freezing ovarian tissue; is preferred in patients who do not have time for drug treatment, mostly in children. A part of the egg tissue is taken by laparoscopy and stored. How is freezing? Beginning of egg freezing; The test tube is as treatment protocol. First, the eggs are grown appropriately or the eggs are followed in natural cycles and then the eggs are collected and stored. The eggs obtained are frozen by various freezing techniques. Especially in recent years, rapid freezing (vitrification) has been successful. Vitrification is currently achieved in embryos and eggs after thawing up to 100 percent viability. For a short time, the cell is protected by creating a glass surface around the cell by providing sudden heat drop with high concentration of freezing solutions. Approximately two weeks before starting chemotherapy or radiotherapy, the ovaries are stimulated and egg growth is achieved. In breast cancer cases, because the hormone receptor is positive, if the cancer is sensitive to estrogen, the estrogen used to stimulate the ovaries is kept low. When you can get pregnant or start treatment after cancer treatment depends on the type of cancer, stage and duration of the drug. After an adequate dose of the drug is provided, it is allowed for pregnancy if there are no signs of cancer in X-rays, MRI and blood tests in cancer screening. According to the regulation of reproductive techniques of the Ministry of Health; embryo and egg storage period is determined as five years and only in some special cases the requirement to be extended. Married couples can do embryo freezing with IVF treatment. If there is an embryo suitable for the remaining freeze after embryo transfer, the pairs can also be frozen with permission. Egg freezing was used only in cancer patients in the past. However, in the last months of 2014, with the amendment of the in vitro fertilization regulation by the Ministry of Health, it was allowed to freeze the eggs, provided that the ovarian reserve decreased or the risk of early menopause was proved at an early age. After chemotherapy, menstruation can be reversed for at least 6-12 months. The improvement of menstruation does not always mean that pregnancy can be achieved. FSH, E2 (estradiol) and AMH (antimullary hormone) tests should be performed on the third day of menstruation to determine whether ovarian function is affected by treatment. How successful is the freezing process?Pregnancies and live births have been reported with frozen eggs and placing ovarian tissue in different parts of the body. Increasing survival rates with advances in technology and cancer treatments; It also provides protection of fertility. The chemotherapy and radiotherapy used affect the ovarian functions in women and lead to early menopause, which we call early egg failure. For this reason, it is important that oncologists consider the desire of the child before treatment and for the future of their patients. of patients; IVF specialists, radiation and medical oncologists should be evaluated and informed about infertility prevention methods. A treatment protocol should be established considering the psychology and thoughts of the patient.